Chen J, Li L, Chen SR, Chen H, Xie JD, Sirrieh RE, MacLean DM, Zhang Y, Zhou MH, Jayaraman V, Pan HL. “The a2d-1-NMDA Receptor Complex is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions.” Cell Reports
Dolino DM, Chatterjee S, MacLean DM, Flatebo C, Bishop LDC, Shaikh SA, Landes CF and Jayaraman V. “The structure-energy landscape of NMDA receptor gating.” Nat. Chem. Biology
Coombs ID*, MacLean DM*, Jayaraman V, Farrant M and Cull-Candy SG. “Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation.” Cell Reports
MacLean DM, Jayaraman V. “Deactivation kinetics of Acid Sensing Ion Channel 1a are strongly pH-sensitive.” PNAS
Vitrac H, MacLean DM, Karlstaedt A, Taegtmeyer H, Jayaraman V, Bogdanov M, Dowhan W. “Dynamic lipid-dependent modulation of protein topology by post-translational phosphorylation.” JBC
Shaikh SA, Dolino DM, Lee G, Chatterjee S, MacLean DM, Flatebo C, Landes C, Jayaraman, V. “Stargazin modulation of AMPA receptors.” Cell Reports
MacLean DM, Jayaraman V. “Acid Sensing Ion Channels are tuned to follow high frequency stimuli.” J Physiol.
Vitrac H, MacLean DM, Bogdanov M, Jayaraman V, Dowhan W. “Dynamic membrane protein topological switching upon changes in lipid environment.” PNAS
Sirrieh RE, MacLean DM, Jayaraman V. “A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc.” JGP
Sirrieh RE, MacLean DM, Jayaraman V. “Subtype-dependent N-methyl-D-aspartate receptor amino-terminal domain conformations and modulation by spermine.” JBC
MacLean DM. “Constructing a rapid solution exchange system.” Ionotropic Glutamate Receptor Technologies.
MacLean DM, Ramaswamy S, Du M, Howe J, Jayaraman V. “Stargazin promotes closure of the AMPA receptor ligand-binding domain.” JGP
Lee G*, MacLean DM*, Ulrich H, Zhao C, Aronowski J, Jayaraman V. “RNA based antagonism of NMDA receptors.” ACS Chem Neurosci.
Ramaswamy S, MacLean DM, Gorfe AA, Jayaraman V. “Proton-mediated conformational changes in an acid-sensing ion channel.” JBC
MacLean DM. “TARPs modulate AMPA receptor conformations before the gating transitions.” J Physiol.
Sirrieh RE, MacLean DM, Jayaraman V. “Amino-terminal domain tetramer organization and structural effects of zinc binding in the NMDA receptor.” JBC
Ramaswamy S, Cooper D, Poddar N, MacLean DM, Rambhadran A, Taylor JN, Uhm H, Landes CF, Jayaraman V. “Role of conformational dynamics in alpha-amino-3-hydroxy-5-methylisoxazole-4-propinoic acid (AMPA) receptor partial agonism.” JBC
MacLean DM, Bowie D. “TARP modulation of AMPA receptor pharmacology: A problem of interpretation.” J Physiol.
MacLean DM, Wong AY, Fay AM, Bowie D. “Cations but not anions regulate the responsiveness to Kainate receptor agonists.” J NRS
Wong AY, MacLean DM, Bowie D. “Na+/Cl- dipole couples agonist binding to Kainate receptor activation.” J NRS
Kuang D, Yao Y, MacLean DM, Wang M, Hampson DR, Chang BS. “Ancestral reconstruction of the ligand binding pocket of family C G-protein coupled receptors.” PNAS